Sunday, June 7, 2009

DNA : The Genetic material

1) What is the genetic material?

The Hammerling Experiment: Cells Store Hereditary Information in the Nucleus

• Hammerling conducted a series of experiments and discovered that hereditary information in Acetabularia resided in the foot, which is also the location of the nucleus.

Transplantation Experiments: Each Cell Contains a Full Set of Genetic Instructions
• Later experiments in the mid-1950s showed that the nucleus of eukaryotic cells includes a full set of genetic information.

The Griffith Experiment: Hereditary Information Can Pass Between Organisms
• Griffith found that transformation occurs when genetic material is transferred from one cell to another, and that live cells can be transformed by dead cells.

The Avery and Hershey-Chase Experiments: The Active Principle Is DNA
• Avery provided conclusive evidence that DNA is the heredity material for the bacterial specimens under investigation.
• Hershey and Chase provided further evidence that heredity material in bacteriophages was found in DNA, not in proteins.

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